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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eafc3ab50e1f89b07efb699e3946d34dd961a72b053a1d68380ccd9d12b394b' 
  AND token = 'riUFY9m+UK7IbvECUhqx/wQoIdIPvc9sy95ibvVcWCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}