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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43894600916609db38c4eac4b039a815bbfa2543d9a9b3e50c5b3404e904baf' 
  AND token = 'd9wxYtYfdIae+OHPK0XmqpgtGIO/UnMc0XRjRZKwb1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}