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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68654e14faff87f68556c3a8345ef1c7350c5ca3c22ca8381928d2f559a47ba6' 
  AND token = 'Ekj70yXfUMaNhn0X8CitW4WNTKiDE/FIVVtd8qhnrvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}