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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a69f5a3f844a1ebe591218ae18c7d96fb371ecf17596b0151427308f113069f' 
  AND token = '64R66E5G13W/B+a/+9NVSi3HRfm4MMKdcZ8z8o5C6Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}