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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d21ffaf43000e16e0d33bc7d9b688ae95015009dc7bf124772844f36a0f4e2d' 
  AND token = 'rof8zgZDq3G7kOdRWJoOW89z6oB4YpSHphblu+dcWwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}