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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efae1da02cfcbe623ddb89750679aab014c7ec1d2b2040ac796cee69028e338b' 
  AND token = 'Ilx09phsWRv3g2afYsXelvv9BcmBBWw/zeaa8kNluIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}