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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287a135022811cd5e6c433f6708e2470b5173d76f1e9ed8e4bc343aaf28e5f84' 
  AND token = 'sFbg5y6xRw+KZpz4a8LQDOLudt7gJb058bAfwQptSV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}