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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fb6a580fc48353b2c805e5dd0238b102e94204332c54baddf57c84d509948d' 
  AND token = '44OQT16oYid3cC5NOlE3G/eK4ZV+HbwbsxQDBhUTXZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}