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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01783f2b38c00b5cf39b4d28e1c8cbac6c17ee6a7881cd35a48316ec8c3bd48b' 
  AND token = 'fMUoY5wkCxh9dw8Zxc/zjjEiAi4qm6ntoETIz86K4fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}