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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ffdf83887df6870cb3f083fc85c7d3a13343e615846a2bc10d525d80157a16' 
  AND token = 'ygmAxkV50tNFfBg1cnzGj08v0RO0DGdEG2WyFLgj74g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}