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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72789b29dbaa91058cb616a159fea3c60814a6e3e43d75a7403dc51e572262c5' 
  AND token = 'IQuDX9cn64ZszyEEUyBKKETgRC44n0pzKcsfyoPAD3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}