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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1bbbbfb1833b2ce3a1e8930309b8bee195fa5dbdcf9311d849096bda8662f1' 
  AND token = 'oUg9ub3KNYll8/m6VKV5HSNmrpy0z/z25sFHs6mxLDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}