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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ce7de86a6476713c9d964154b8d8485b55f1a799ebfe542859501c9a78679c' 
  AND token = '7/QgRiI9uoy0LJJNYfkzi889URwpWPDRGSDgQGqRmko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}