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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447959c769818fd6128675018a01713007c66e2c0ef6040828669d8e213d75d3' 
  AND token = 'bVAvlnN2lniFGRdgf0TlcxWnHu03+okuDhNBwR2UwPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}