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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455c25bb56db8f120c3831b07515a41be0e680005a366017843e11a00ce03ac6' 
  AND token = 'vaN8kI4McLRdJajzn/jFQKxKdGYYYqquTqeJM1s1/9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}