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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31db9fc4856117bb70f09bbe48be0caaeaa9c1e1fd0ca3daaab746bb49f4762b' 
  AND token = '450aWBQVaciqPKjPQacUkuD6R+k14upJsx7kfdoVNvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}