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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2456fc0b784b6aeeddc8ffb5b0a536284159096592551b1a4ba61c267c987942' 
  AND token = '8V2AWDXzP4SVjizmNgtQjiNDn3ug3AK3lQY7yJTxm3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}