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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90f011395f204090a465dd5afa9bf630d99547be6dd22f8263256d2ac323b2d5' 
  AND token = '0wHwH2l+6hRHTHCtb+qMo0+t8OussbHR9GA53iJbWMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}