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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3073a0fd712b25aebda3e5d8a6b829efd5522d658ba66c7a1f992e424a07d9c1' 
  AND token = 'lfgAlG5FA/bPb/q0OzI+9ISSn7v5GFBmGCdY/L53Qrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}