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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5a5ccaec2f1276061ef165f5bb9114bdd8e8b643b03006a7971fc3709b9aba' 
  AND token = 'pez+DKgLEYFUCLBny38YTt6jU15mUpzOlebbID1bd3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}