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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e576e5358aa34f84ff9113b6669986e07ca865311ef3b6f80c73894d035a252' 
  AND token = 'Y9LFI1V7c6dl0t0lLQBqIx8fNENMUHhSiOjUP/a9Uz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}