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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99218970af5a1263951c01921baf55968aaa537beba53846d8dd2767072f87d3' 
  AND token = 'ZB1tw+X9A36Z+0a0nGt9v7e53DgbM8gxwUNjwBQXroI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}