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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '109b2cce543758244c6ec45e9c5e495829df972c1015091511f1a68c298a3517' 
  AND token = 'YrbxJ0hZbrpxO9ZovSOpaXbcz6oUWorj5GcRymxbGKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}