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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217ba1e6536885024a8411822827e4b4e098d7dcdf6e144bc903b50fb409679f' 
  AND token = 'YSNXD0PYoUD44P0sbYgVc1ocvcq4wE4iMFiP59XwTeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}