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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2eb1a3b11544eb05709ac15be048c6e359c5c1d05157df49d8d1a3321c1bab' 
  AND token = 'cZTVXykYFKqBcKq3Va54E6PO+O5o3MDJTDZ3A0004So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}