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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a5a91757e3c8c50656c15370ec7b007fd1f56a719ca88ac51859af6036562c' 
  AND token = 'Q3bI65+I04A6IYJh6wGVAKYsZxT6Q3wP9WjvnC6/d3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}