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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca70eb27883442776aaae8eb8fdf81de25cf20af017e8081b7e4bfaae2183d5' 
  AND token = 'EloIByV4s48wqGzvrwE1HbLgACgDqartUWq1Jf3NAck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}