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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fbd182ce0a46a105e665cb52ba1082f8e85b2965ba1e0c1f6432dc8cbc73196' 
  AND token = 'WI7raJuJzP966yhjRe4a5SZcOVefIWCA7qMUeyoFUxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}