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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a23a08868ffbc5b7684d3ef231168ff16415656b4f36694e3ef63ae2ddbda1' 
  AND token = 'eJUOxS82BHv0fV+94wfc6BiLyxt2rKwYVy+SQsoch+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}