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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4784065cfce7d286d72933bad15c30e5363035c1f95f6e37b1517096db6b03b8' 
  AND token = 'JR1bx28LXnwkz/KGcUS4fFwiyo5rkIe+k/VOGokIJUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}