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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3623356c71976a6c9270ea063a7a34d2a69ae20ed4f7ceb40ef46e84f02ee279' 
  AND token = '51soElEegaHrPcsTlzFNxvYUhGAajIznvqldRcgKm6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}