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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2a878777c568c629537e9297bea1dd7f10eb3d1dcb587e0ff2b6e6e6c76d8ff' 
  AND token = 'BPy+v9kysGrx8lmoLcQFu0mWOZ2odOrCCQuWpavnPR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}