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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f51c44c55f2d72152c8097153e677b95c8040f2410e16402dfb42f8aba3dabf5' 
  AND token = 'P1j6FAWA8/vevruOwZd6vGSFweixm3NZTvWSr00Oni4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}