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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492b10ae283b34dec9bce1484639eeca5bb48e015297e2060c0fbc0b4bf844b3' 
  AND token = '/kBueDBoPLwWRA/26jlBuKYak/HrzezdaOpE3W2QVco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}