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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7457dd0a115e19ae3ba59d64507d6ee6849e4e225b7dd5300f99247dec49c7e8' 
  AND token = 'q4TS6m20XyOU7Tu6/dVQ3Lez3mDrYz6rsdsF3XF4g9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}