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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d48ee17f9124f28a803fa9c4d407e66d092635197d8d0dffdbad59c4d63a3af' 
  AND token = 'soulE7Ooc720THjidlXGrJQHglVk7uIee9nbNVxB64Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}