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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f893c017903218ee828b2bff12ee99fc2696c1794b5baf1b7a9e9956fe17644' 
  AND token = 'OMKC0Uk0oIvUlCVKhHTw4YS+Ktwd759/Ksvp4k3HN7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}