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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '696e23e726691c6b2d058dd4090e7075d0d0cc2547924694bca8b8f9fae72196' 
  AND token = '4Fwloe6yZ6cQkOVHlFAotArfx/W2/yACs+GaDNPeK6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}