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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bd1f79b1bb6beb479a7cef782a680bda8c082d0ebcef5d2c2f6d867681d6d6' 
  AND token = '6+L42qrgRvS1zff8CD1JaaR5s2LILAOMXOLE72K+cUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}