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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204a59522b4192b1a6821863556f635150db7aab64d63665eee4e8aa3125008a' 
  AND token = 'Lp945nfOnOmpXwtIlPlV5BiO6dRerZYWgLLTunvtDQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}