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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f456f44c286302864bffb2f87baf46ce69c820cbf67850b557e2303c8bf990ac' 
  AND token = 'yD5TzY6269SQsd+gBA0rbo+ZmGAA6NcHlU21WTBfNmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}