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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '473f685c74cd23908160714144c577123da72c8618693e709e422aa8cab589e1' 
  AND token = '8u/pgL7dpoV7fl8Xla/P2FTQKPqUbZvs/aMky0XIH0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}