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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57eb2db636c508f9500f79cc0c1f3a3f2b2f3e2dec833150490a56731e05c2ac' 
  AND token = 'fE0x1VwRG3f2BVs0uEf4XB9oRxYS2SenteXyRWrxaOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}