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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab3c836f6536cd87e5c51697551627b26f814567ce0ec3de4d06cc8b4246be48' 
  AND token = 'BTWDDI3jVcht7A1HurFuqf1IDiNLcKa+1NNpmkYfIrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}