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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e97b41cd8746f98485fff284b0adc85989962058f321ede2f5503d87a10579' 
  AND token = 'Tp3P+offUL+G0n62vfF3ppHyqMFMRGYPV55n4SmYdp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}