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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e64de195b4fc8afcf1a6765261b7afb4382c59d7cb1d184f93820efe8416a8' 
  AND token = 'A7cAFw8Z1dJTXl6FkLvJ9vTO2t+GsTyW3aAbRVqjc4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}