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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5776dcd31a46c041888203af88cfd2ce24a8d59f2d0bdea84b3b5e92c14c4b' 
  AND token = 'mdGgD7MTFvkEImbLob/Fxf4Ra6Mx42T3+sJpW0UALcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}