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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c38413a9d19f6bc7de328cb876958334b56eae8cb15b77f5ad6b31d61447c51' 
  AND token = 'PpLa/j9T1x6XTL0ADcJT/mCxi3R/zxJv7YngnvAEjAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}