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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '364881f96494ef4e68c03ee6750949b5de5e075cf3600c1f2fbab3d7e37af54e' 
  AND token = 'CGM5nQFkRz5oPNLPbkG+GNK/Hupl1KP4cXqZreH14Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}