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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1056e3e96d83c199655cba1508a4e50b5c1f98c34deab82a13ddaf7956515b06' 
  AND token = 'fayxQ+MCzSnKFOtb7theiKzoiz5GsPLYjO5q8zaE3mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}